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What effect does isotretinoin have on the skin?

  1. Increases oil production

  2. Reduces skin sensitivity

  3. Increases skin sensitivity and dryness

  4. Heals skin wounds

The correct answer is: Increases skin sensitivity and dryness

Isotretinoin is a powerful medication primarily used to treat severe acne. One of the well-documented effects of isotretinoin on the skin is its ability to significantly decrease oil production from sebaceous glands. This reduction leads to not only less oily skin but also lower acne occurrence. Additionally, isotretinoin has a range of side effects, among which increased skin sensitivity and dryness are prominent. Decreased oil production causes the skin to become drier because the natural oils that provide moisture and barrier protection are diminished. This dryness can often lead to increased sensitivity, making the skin more prone to reactions and irritation from external products and environmental factors. Therefore, understanding that isotretinoin works by altering the skin's oil production and overall moisture balance is essential in recognizing its primary effects, which include increased skin sensitivity and dryness. The other responses do not accurately depict the effects of isotretinoin, as it does not increase oil production, it does not inherently reduce skin sensitivity, nor is it specifically targeted for wound healing purposes. Thus, the assertion that isotretinoin increases sensitivity and dryness captures the significant dermatological impacts of this medication.